{"id":2,"date":"2024-07-11T20:53:16","date_gmt":"2024-07-11T20:53:16","guid":{"rendered":"https:\/\/myweb.fiu.edu\/dgoldwas\/?page_id=2"},"modified":"2024-07-19T15:59:26","modified_gmt":"2024-07-19T15:59:26","slug":"sample-page","status":"publish","type":"page","link":"https:\/\/myweb.fiu.edu\/dgoldwas\/sample-page\/","title":{"rendered":"Cancer Research"},"content":{"rendered":"<h2><\/h2>\n\n\n<p><strong><em>\u201cYou have enemies? Good. That means you&#8217;ve stood up for something, sometime in your life.\u201d<\/em> Winston Churchill.<\/strong><\/p>\n\n\n\n<p>My research focuses on mathematical models of lung cancer screening and bioinformatics.<\/p>\n\n\n\n<p>I was able to demonstrate that the tumor size at stage transition for aggressive lung cancers is smaller than previous studies indicate: as small as 10 mm for male smokers and 15 mm for female smokers, underscoring the aggressive nature of lung cancer and the difficulties of early detection. &nbsp;I further demonstrated that several mathematical fallacies persistent in the literature have precluded these estimates, despite their compatibility with data over a wide range of lung cancer data sets. A summary of my findings are presented here:<\/p>\n\n\n\n<p><a href=\"https:\/\/vimeo.com\/\/775642323\">Debunking Mathematical Fallacies in Models of Lung Cancer Screening<\/a><\/p>\n\n\n\n<p>My current research goals are:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Assess screening effectiveness among various lung cancer screening protocols in light of a mathematical model for the underlying natural history of lung cancer in which the size at stage transition is small.<\/li>\n\n\n\n<li>Examine estimates of mathematical models of the underlying natural history of breast cancer for accuracy across a range of data sets.<\/li>\n\n\n\n<li>Consider ways that single cell sequencing data may improve early detection of lung cancer, in particular with respect to the resolution of small nodules.<\/li>\n<\/ul>\n\n\n\n<p><strong>Selected First and Sole-Author Publications:<\/strong><\/p>\n\n\n\n<p><strong>Goldwasser DL.<\/strong> Estimation of the Tumor Size at Cure Threshold among Aggressive non-small cell lung cancers (NSCLCs): Evidence from the Surveillance, Epidemiology, and End Results (SEER) program and the National Lung Screening Trial (NLST). <em>Int J. Cancer<\/em>. 2017; 140(6): 1280-1292.<\/p>\n\n\n\n<p><strong>Goldwasser DL<\/strong>, Kimmel M. Small Median Tumor Diameter at Cure Threshold (\\textless 20 mm) among Aggressive Non-Small Cell Lung Cancers in Male Smokers Predicts Both Chest X-Ray and CT Screening Outcomes in a Novel Simulation Framework. <em>Int J. Cancer<\/em>. 2013; 132(1): 189-197.<\/p>\n\n\n\n<p><strong>Goldwasser DL<\/strong>, Kimmel M. Modeling Excess Lung Cancer Risk among Screened Arm Participants in the Mayo Lung Project. <em>Cancer<\/em>. 2010; 116(1):122-131.<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u201cYou have enemies? Good. That means you&#8217;ve stood up for something, sometime in your life.\u201d Winston Churchill. My research focuses on mathematical models of lung cancer screening and bioinformatics. I <a class=\"more-link\" href=\"https:\/\/myweb.fiu.edu\/dgoldwas\/sample-page\/\">Continue Reading &rarr;<\/a><\/p>\n","protected":false},"author":6515,"featured_media":0,"parent":0,"menu_order":2,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-2","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/myweb.fiu.edu\/dgoldwas\/wp-json\/wp\/v2\/pages\/2","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/myweb.fiu.edu\/dgoldwas\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/myweb.fiu.edu\/dgoldwas\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/myweb.fiu.edu\/dgoldwas\/wp-json\/wp\/v2\/users\/6515"}],"replies":[{"embeddable":true,"href":"https:\/\/myweb.fiu.edu\/dgoldwas\/wp-json\/wp\/v2\/comments?post=2"}],"version-history":[{"count":0,"href":"https:\/\/myweb.fiu.edu\/dgoldwas\/wp-json\/wp\/v2\/pages\/2\/revisions"}],"wp:attachment":[{"href":"https:\/\/myweb.fiu.edu\/dgoldwas\/wp-json\/wp\/v2\/media?parent=2"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}